Presented by Julia Malkowski, ND, DC | April 1, 2026 at 12 PM Pacific

Methylation is a fundamental biochemical process with far-reaching implications for human health. This presentation will offer an in-depth exploration of methylation, its clinical significance, and the impact of methylation imbalances on health outcomes.

Methylation is involved in cardiovascular health, detoxification, neurotransmitter synthesis, hormone metabolism, DNA expression, immune modulation and fetal development. Analyzing key methylation biomarkers provides valuable insight into human physiology. Plasma levels of methionine, s-Adenosyl methionine (SAM), s-Adenosyl homocysteine (SAH), homocysteine, cystathionine and cysteine provide a functional assessment of the methylation cycle. Attendees will walk away with an understating of these biomarkers, enhanced understanding of methylation dynamics and their impact on clinical outcomes.

Learning Objectives:

• Understand the role of methylation in human physiology
• Comprehend objective biomarkers of the methylation cycle, including the methylation ratio, methionine, SAM, SAH, homocysteine, cystathionine and cysteine
• Explore the clinical significance of methylation imbalances
• Discuss case applications and therapeutic strategies based on methylation status